Physico-chemical properties of sputum in reversible airways obstruction.
نویسندگان
چکیده
منابع مشابه
Exacerbations of asthma without sputum eosinophilia.
BACKGROUND Sputum analysis provides a non-invasive method of examining the airway secretions of subjects with asthma in order to better understand the inflammatory process. Increased proportions of eosinophils are generally seen in the sputum of subjects with asthma, especially when there is an exacerbation. An unexpected observation in the sputum of subjects with mild exacerbations of asthma i...
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Increased arginase activity contributes to airway nitric oxide (NO) deficiency in cystic fibrosis (CF). Whether down-stream products of arginase activity contribute to CF lung disease is currently unknown. The objective of this study was to test whether L-ornithine derived polyamines are present in CF airways and contribute to airway pathophysiology. Polyamine concentrations were measured in sp...
متن کاملAssessment of airways inflammation in chronic bronchitis.
Chronic bronchitis is a clinical syndrome, defined on the basis of sputum production [1, 2]. Investigations have demonstrated that airway inflammation is central to the clinical changes associated with chronic bronchitis. Histological investigations of surgical and autopsy specimens have provided material to determine the site and nature of the airway inflammation. Sampling of the airways via f...
متن کاملAirways obstruction, chronic expectoration, and rapid decline of FEV1 in smokers are associated with increased levels of sputum neutrophils.
BACKGROUND Smoking may cause inflammation of the airways and impairment of lung function. To determine the relationship between the type and degree of airways inflammation and the decline in lung function, leucocytes in the sputum of smokers and ex-smokers were examined. METHODS Forty six smokers and ex-smokers of median age 64 years (25%; 75% percentiles 62;66) with a smoking history of 40.1...
متن کاملFarming and the prevalence of non-reversible airways obstruction: results from a population-based study.
INTRODUCTION Occupational exposure to noxious dusts, gases, and fumes most likely contributes to obstructive lung disease. We studied whether self-reported farming work is associated with non-reversible airways obstruction. METHODS Following the burden of obstructive lung disease (BOLD) study protocol, we surveyed a gender-stratified population-based sample of 2,200 adults aged 40 years and o...
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ورودعنوان ژورنال:
- Chest
دوره 63 شماره
صفحات -
تاریخ انتشار 1973